Clinical Trials of Adult T-Cell Leukaemia/Lymphoma Treatment
نویسندگان
چکیده
منابع مشابه
Clinical Trials of Adult T-Cell Leukaemia/Lymphoma Treatment
Adult T-cell leukaemia/lymphoma (ATLL) is an aggressive malignancy of mature activated T cells caused by human T-cell lymphotropic virus type I (HTLV-1). Prognosis is severe because of intrinsic chemoresistance and severe immuosuppression. Four different subtypes are described with different outcomes, and treatment strategies vary according to the different clinical courses. Japanese trials sho...
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The treatment strategy for adult T-cell leukemia has not been established. CHOP derived combination chemotherapy protocols such as VEPA and VEPAM have failed to yield high complete remission rates and long survivals. Second or third generation combination chemotherapy regimens using alternative non-cross resistant drugs also have not achieved satisfactory results. A new multi-institutional tria...
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1Third Department of Internal Medicine, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki; 2Department of Molecular Medicine and Hematology, Molecular Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki; 3Department of Nutritional Health, Faculty of Wellness Studies, Kwassui Women’s College, Nagasaki; 4Division of Cytokine Sign...
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ژورنال
عنوان ژورنال: Leukemia Research and Treatment
سال: 2012
ISSN: 2090-3219,2090-3227
DOI: 10.1155/2012/932175